The new direction in pain treatment after surgery
Our mission
We aim to make a difference for the millions of patients facing acute postsurgical pain each year and contribute to a more affordable healthcare system, where opioids are no longer the norm
Spinal fusion surgery: the largest unmet need
Spinal disorders are often treated by fixating segments of the spine with pedicle screws. Implantation of the screws unavoidably causes debilitating pain for multiple days. Patients currently receive opioids in high doses. Pain and the many opioid-related side effects hamper recovery and extend hospital stays
Although the negative effects of opioids are globally recognized, no viable alternatives in postsurgical pain treatment have come to clinical practice
Our lead product: BR-003
A unique highly elastic and biodegradable hydrogel releasing a powerful local anesthetic for multiple days
Designed to be attached to commercially available screws used in spinal surgery
Our lead product: BR-003
A unique highly elastic and biodegradable hydrogel releasing a powerful local anesthetic for multiple days
Designed to be attached to commercially available screws used in spinal surgery
Seamless integration with the existing surgical workflow
BR-003 is simply co-implanted without changing the placement or function of the screw
The surgical procedure remains identical otherwise
Optimal placement
BR-003 is strategically placed at the location where it can effectively and reliably target the essential pain nerve fibres
Locally blocking pain signals
BR-003 releases bupivacaine for 72+ hours. Bupivacaine is a safe and effective anesthetic that locally blocks pain signals and is well known for its use in dentistry and epidural analgesia
Adding value at every level
Patients: fewer opioids for faster and better recovery
Care Providers: better outcomes and higher patient satisfaction
Hospitals: less strain on capacity, more predictable planning, lower costs
Society: lower risk of chronic pain and opioid addiction