The new direction in pain treatment after surgery

Our mission

We aim to make a difference for the millions of patients facing acute postsurgical pain each year and contribute to a more affordable healthcare system, where opioids are no longer the norm

Spinal fusion surgery: the largest unmet need

Spinal disorders are often treated by fixating segments of the spine with pedicle screws. Implantation of the screws unavoidably causes debilitating pain for multiple days. Patients currently receive opioids in high doses. Pain and the many opioid-related side effects hamper recovery and extend hospital stays

Although the negative effects of opioids are globally recognized, no viable alternatives in postsurgical pain treatment have come to clinical practice

Our lead product: BR-003

A unique highly elastic and biodegradable hydrogel releasing a powerful local anesthetic for multiple days

Designed to be attached to commercially available screws used in spinal surgery

Our lead product: BR-003

A unique highly elastic and biodegradable hydrogel releasing a powerful local anesthetic for multiple days

Designed to be attached to commercially available screws used in spinal surgery

Seamless integration with the existing surgical workflow

BR-003 is simply co-implanted without changing the placement or function of the screw

The surgical procedure remains identical otherwise

Optimal placement

BR-003 is strategically placed at the location where it can effectively and reliably target the essential pain nerve fibres

Locally blocking pain signals

BR-003 releases bupivacaine for 72+ hours. Bupivacaine is a safe and effective anesthetic that locally blocks pain signals and is well known for its use in dentistry and epidural analgesia

Adding value at every level

Patients: fewer opioids for faster and better recovery

Care Providers
: better outcomes and higher patient satisfaction

Hospitals
: less strain on capacity, more predictable planning, lower costs

Society
: lower risk of chronic pain and opioid addiction